Jobelyn is a natural product made from Sorghum bicolor extract that has been shown to have potential therapeutic benefits for individuals with autoimmune disorders like arthritis. Jobelyn is listed in the drug dictionary of the National Cancer Institute and is defined as a dietary supplement made from Sorghum bicolor extract that has anti-inflammatory and antioxidant properties.
Sorghum bicolor supplement containing Sorghum leaf sheath extract and Jobelyn can be used as a natural approach to supporting arthritis care. Sorghum grains and leaf sheaths extract can be prepared and used as a dietary supplement. Jobelyn can be taken as a dietary supplement in capsule form.
Several clinical and in vitro studies have been done on Sorghum polyphenols and their potential benefits for autoimmune disorders. One study published in the Journal of Medicinal Food in 2016 found that Sorghum extract reduced inflammation and improved joint function in rats with arthritis. Another study published in the Journal of Agricultural and Food Chemistry in 2017 found that Sorghum leaf sheath extracts had anti-inflammatory effects in human immune cells. A study published in Joint Bone Spine in 2017 found that Jobelyn reduced paw edema and pain sensitivity in mice with arthritis, and improved their neurobehavioral deficits. A study published in Clinical and Experimental Rheumatology in 2019 found that apigenin and apigeninidin, two polyphenolic compounds found in Sorghum bicolor, were able to inhibit the production of inflammatory mediators that contribute to the development of autoimmune disorders.
Sorghum bicolor supplement containing Sorghum leaf sheath extract and Jobelyn may offer a natural approach to supporting arthritis care. Sorghum polyphenols have been shown to have potential anti-inflammatory and antioxidant effects, and Jobelyn has been shown to have potential therapeutic benefits for individuals with autoimmune disorders like arthritis. While more research is needed to confirm these findings and determine the optimal dosage and duration of treatment, incorporating Sorghum polyphenols into an arthritis care regimen may provide complementary support for conventional treatments.
● A powerful antioxidant-rich supplement made of sorghum bicolor leaf extract
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Sorghum phytochemicals and their potential impact on human health
Polyphenols in the treatment of autoimmune diseases
Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclo-oxygenase-2 and prostaglandin-E2 blockade" demonstrated the effects of Jobelyn isolates.
Freund-adjuvant-induced arthritis in mice
Jobelyn® exhibited anti-inflammatory, antioxidant, and membrane-stabilizing activities in experimental models
Sorghum Research Reviews and Meta-analysis
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Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials