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Natural treatment for chronic inflammation: Polyphenol-rich Sorghum bicolor leaves extract

Updated: Oct 1, 2023



Natural treatment for chronic inflammation: Sorghum bicolor leaves extract 4X more powerful than Acai berries Millions of people battle constant tiredness, brain fog, pain, and inflammation every day. Having chronic inflammation compromises our immunity. It also increases our risk of developing one or more chronic diseases. Even low-grade inflammation over a while can lead to issues like high blood pressure, diabetes, arthritis, psoriasis, depression, digestive problems, and other conditions. And there is no cure. Sure, medications can help manage symptoms of chronic inflammation. But, over time, taking many pills brings different challenges. Each pill has its own side effects, and many drugs interacting together can also affect the body. It’s no surprise that many are turning to natural remedies for relief. And the medical community is also getting on board. Nowadays, there is more research into plant-based therapies to treat chronic conditions.


Science has proven that chronic, low-grade inflammation can turn into a silent killer that contributes to cardiovas­cular disease, cancer, type 2 diabetes and other conditions. 

The fact that three out of five people around the world die from a disease linked to inflammation raises serious red flags.


Discover the highly effective ways to ways to tame inflammation and help:

  • Treat asthma and allergies 

  • Treat autoimmune diseases—IBD, rheumatoid arthritis, lupus, multiple sclerosis, and psoriasis 

  • Protect your heart

  • Protect your brain from dementia, depression & stroke

  • Combat inflammation in metabolic diseases

  • Fight against cancer

  • Treat Sickle-cell anaemia Disorder. A natural treatment for chronic inflammation One such treatment for chronic inflammation is the Sorghum bicolor leaf — a powerful herb rich in polyphenols. Polyphenols are packed with antioxidants, and a diet rich in polyphenols boosts the immune system. They can help protect us from chronic diseases and autoimmune conditions like: ● Cardiovascular disease and stroke ● Diabetes ● Arthritis ● Cancer ● Chronic viral infections

  • Sickle-cell anaemia disorder ● Anemia, and much more.




In recent years, dietary polyphenols have gained significant interest among researchers due to their potential chemopreventive/protective functions in the maintenance of human health and diseases. It is believed that dietary polyphenols/flavonoids exert powerful antioxidant action for protection against reactive oxygen species (ROS)/cellular oxidative stress (OS) towards the prevention of OS-related pathological conditions or diseases. Pre-clinical and clinical evidence strongly suggest that long term consumption of diets rich in polyphenols offer protection against the development of various chronic diseases such as neurodegenerative diseases, cardiovascular diseases (CVDs), cancer, diabetes, inflammatory disorders and infectious illness.


Rheumatic diseases (RDs) belong to a group of chronic musculoskeletal pathological conditions characterized by joint damage, inflammation, pain, functional disability and impact on individuals’ quality of life. Rheumatic diseases include chronic clinical conditions of multi causal etiopathogenesis characterized by disruption of immunological tolerance, production of autoantibodies, production of a number of substances accounting for lesions in many body structures,

mechanical stress in the joints and changes to the alignment of bones, cartilage and other structures necessary for joint stability.

They give rise to a heterogeneous group of clinical conditions, such as rheumatoid arthritis, osteoarthritis, scleroderma, systemic sclerosis, ankylosing spondylitis, fibromyalgia, osteoporosis, tendinitis, gout and lupus, among others. Osteoarthritis (OA) and rheumatoid arthritis (RA) are the most common RDs.

OA is the first chronic, inflammatory and degenerative disease that arises through joint cartilage wear or loss. RA is an inflammatory disease that mainly affects joints without being degenerative. Instead, it causes structural damage and joint inflammation, which result in progressive structural and functional losses.



What is Sorghum Bicolor Leaf? What are its benefits? Sorghum bicolor leaf is a type of gluten-free grass filled with nutritional value. It is popular in many countries in Africa for its anti-inflammatory. In recent years, in vitro studies have shown that flavonoids and polyphenols in sorghum bicolor leaf extract give it antimicrobial effects when exposed to certain bacteria and can even inhibit the human immunodeficiency virus (HIV). Jobelyn® is a Sorghum Bicolor Leaf supplement for chronic inflammation. Built on extensive research, Jobelyn® is designed to help: ● Boost anti-inflammatory effects ● Improve immune system function ● Lower the risk of cancer developing or re-appearing (chemopreventive effect) ● Increase the production of blood cells (hematopoietic effect) ● Reduce pain. (arthritic effect)

How does Sorghum Bicolor Leaf fight inflammation?


Studies show that Jobelyn®, made from sorghum bicolor leaf extract, is over 4 times better than acai berries in quenching free radicals. It is also 50 times better than tart cherries, well-known antioxidants. Tackling free radicals in our body can help delay aging and reduce inflammation. Apart from defusing existing free radicals, Jobelyn® also re-programs inflammatory cells to reduce the number of free radicals produced. It boosts our natural immunity by activating natural killer cells, lymphocytes, and macrophages. These cells are our frontline defense against infection-causing viruses, bacteria, and other foreign bodies. Research shows that the Jobelyn® supplement also selectively increases specific cytokines and chemokines. Cytokines are messenger proteins that ‘alert’ the body about a disease-causing agent and trigger our immune response. Once the body knows it is under attack, chemokines (also proteins) gather the ‘troops.’ They attract disease-fighting cells to the site of infection. Together, these two groups of proteins are an important part of our immune system, and Jobelyn® helps improve our immune response.


Jobelyn® also offers relief from pain. It is a natural COX-2 inhibitor designed to work like ibuprofen and other NSAIDs (non-steroidal anti-inflammatory drugs). COX-2 enzymes in our body create inflammation. COX-2 inhibitors like Jobelyn® target and reduce inflammation, specifically from COX-2 enzymes. These types of medicines work better against pain because they are easier on the stomach and digestive system. Additionally, Jobelyn® is gluten-free. Glutens are types of protein found in wheat, barley, and other grains. Gluten proteins are highly resistant to many of our digestive enzymes — which is why many of us cannot process them. Too much gluten in the diet can cause inflammation and lead to autoimmune disorders like wheat allergy, celiac disease, or different levels of gluten sensitivity. Symptoms can include bloating, digestive issues, headache, fatigue, and pain. This is why gluten-free diets and supplements have become popular in recent years.


According to the National Cancer Institute, USA, Sorghum bicolor leaf is:


“An herbal-based nutritional supplement containing the leaf sheaths of the plant Sorghum bicolor, with potential antioxidant, anti-inflammatory, chemopreventive and immunomodulating activities. Sorghum bicolor supplement contains various phytochemicals, including phenolic acids and polyphenols such as proanthocyanidins. Sorghum bicolor supplement is particularly rich in 3-deoxyanthocyanins, such as luteolinidin and apigeninidin, and appears to induce apoptosis and inhibit cell proliferation in cancer cells through the stimulation of various apoptosis promoter genes and the downregulation of certain apoptosis inhibitor genes. In addition, due to the strong antioxidant nature of the phytochemicals, these compounds are able to scavenge free radicals and prevent tissue damage. Also, intake of this supplement modulates the immune system by both increasing the activity of natural killer (NK) cells and initiating the activation of macrophages.”


How to get Jobelyn® supplements? In West Africa, Sorghum bicolor leaves are used regularly in hot teas, beers, soup, and herbal medicines. However, this well-kept secret was unavailable to the rest of the world, until now. Sorghum leaves are being exported around the world. However, our lives are much busier and more stressful these days. If you’re dealing with chronic inflammation, it can be exhausting trying to manage it all — work, caregiving duties, finances, chores, medical visits, and much more.


You need a simple way to get antioxidant, pain-relieving, and anti-inflammatory effects daily. Jobelyn® can help.




● A powerful antioxidant-rich supplement made of sorghum bicolor leaf extract

● All-natural

● Chemical-free

● Gluten-free Jobelyn® capsules are 50X better than tart cherries and 4X better than Acai berries in fighting oxidation.


How do we know?

We tested them. CAP-e tests are used to measure how well our cells absorb the antioxidants we eat. A CAP-e test demonstrated that human cells respond well to Jobelyn® sorghum bicolor leaf supplements. The test results suggested that Jobelyn® had a complex and wide range of antioxidant properties. Try it now.



to help you fight against chronic inflammation.


Useful References:



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2023 NIH Pain Consortium Symposium on Advances in Pain Research


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Estimated Rates of Incident and Persistent Chronic Pain Among US Adults, 2019-2020



Antioxidant constituents from the stem of Sorghum bicolor Chemical Composition and Antioxidant Profile of Sorghum (Sorghum bicolor (L.) Moench) and Pearl Millet (Pennisetum glaucum (L.) R.Br.) Grains Cultivated in the Far-North Region of Cameroon Enzymes inhibitory property, antioxidant activity and phenolics profile of raw and roasted red sorghum grains in vitro Polyphenolic extract of Sorghum bicolor grains enhances reactive oxygen species detoxification in N-nitrosodiethylamine-treated rats DNA Damage Protecting Activity and Free Radical Scavenging Activity of Anthocyanins from Red Sorghum (Sorghum bicolor) Bran NUTRACEUTICAL USES OF SORGHUM BRAN (SORGHUMBICOLOR) Antioxidant and anti-cancer activities of proanthocyanidins-rich extracts from three varieties of sorghum (Sorghum bicolor) bran Comparison of Content in Phenolic Compounds and Antioxidant Capacity in Grains of White, Red, and Black Sorghum Varieties Grown in the Mediterranean Area Phytochemical screening and antibacterial activities of Sorghum bicolor leaves derived from in vitro culture Nutritional Analysis of Three Commonly Consumed Varieties of Sorghum (Sorghum bicolor L.) in Bauchi State, Nigeria' Evaluation of the health benefits of consumption of extruded tannin sorghum with unfermented probiotic milk in individuals with chronic kidney disease Sorghum: The High-Fiber, Gluten-Free Ancient Grain You Need to Know About https://www.healthline.com/nutrition/sorghum#uses




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2 Comments


Olajuwon Okubena
Olajuwon Okubena
Apr 29, 2023

Thanks for your reply.

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sicklecellnews
Apr 29, 2023

Quite an educational trip! WELLDONE.

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