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Unleashing the Power of 3-Deoxyanthocyanidins: A Promising Sorghum Bicolor Supplement.

Updated: Nov 21, 2023

Harnessing the Power of Sorghum Bicolor: A Promising Supplement Recognized by the NCI


In the quest for alternative approaches to cancer prevention and treatment, scientists have turned their attention to the natural world. One such discovery that holds immense potential is the Sorghum bicolor leaf sheath extract, a supplement rich in 3-deoxyanthocyanins.

This remarkable compound has caught the attention of the National Cancer Institute (NCI), earning recognition in their esteemed drug dictionary.

Let's delve into the significance of this supplement and shed light on its potential benefits.

The NCI Recognition:

The NCI dictionary of drugs lists Sorghum bicolor supplement as an herbal-based nutritional supplement derived from the leaf sheathos of the Sorghum bicolor plant.

This supplement has garnered attention due to its diverse range of phytochemicals, including phenolic acids and polyphenols like proanthocyanidins.

However, what sets it apart is its high concentration of 3-deoxyanthocyanins, such as luteolinidin and apigeninidin.

Potential Benefits:

Research has shown that Sorghum bicolor supplement exhibits antioxidant, anti-inflammatory, chemopreventive, and immunomodulating properties.

Its antioxidant nature enables it to scavenge harmful free radicals, protecting our tissues from damage.

Moreover, this supplement has demonstrated the ability to induce apoptosis (programmed cell death) and inhibit cell proliferation in cancer cells.

It achieves this by stimulating various apoptosis promoter genes while downregulating specific apoptosis inhibitor genes.


One of the most intriguing aspects of Sorghum bicolor supplement is its effect on our immune system.

Clinical studies have indicated that this supplement boosts the activity of natural killer (NK) cells, which play a crucial role in identifying and eliminating cancerous cells.

Additionally, it initiates the activation of macrophages, key players in our immune defense.

This dual action on our immune system could potentially enhance our body's ability to fight cancer.

Promising Outlook:

The recognition of Sorghum bicolor supplement by the NCI is a testament to its potential as a valuable addition to cancer prevention and treatment strategies.

While further research and clinical trials are necessary to fully understand its efficacy and safety, the initial findings are undeniably promising.

With its unique composition and multifaceted benefits, this supplement opens up new avenues in the fight against cancer.


The inclusion of Sorghum bicolor supplement in the NCI drug dictionary highlights its significance and potential impact in the field of oncology.

Its rich content of 3-deoxyanthocyanins, along with its antioxidant and immunomodulating properties, make it a compelling candidate for further investigation.

As we continue to explore natural alternatives, Sorghum bicolor supplement stands out as a beacon of hope, offering a new approach to cancer prevention and treatment.

Let us embrace this discovery and support ongoing research to unlock its full potential.

It is:

● A powerful supplement made of sorghum bicolor leaf extract

● All-natural

● Chemical-free

● Gluten-free

Several clinical and in vitro studies have been done on Sorghum polyphenols and their potential benefits for autoimmune disorders

Try it now :

Sorghum Research Reviews and Meta-analysis

Polyphenols: The Last Nutritional Frontier Increase Health Span, Boost Athletic Performance

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