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Polyphenol-Rich Sorghum Bicolor Supplement, Jobelyn, Could Play a Role in Reversing Stroke.


Stroke is a devastating condition that can lead to severe disability and even death.

As the search for effective treatments continues, modern science is uncovering the potential of natural supplements.

One such supplement, Jobelyn, derived from the polyphenol-rich Sorghum bicolor, shows promise in reversing the effects of stroke.

In this article, we will explore the historical use of Sorghum bicolor, the scientific evidence supporting Jobelyn, and its potential benefits for stroke patients.

Historical Use of Sorghum Bicolor

For centuries, traditional medicine practitioners in Southwestern Nigeria have used Sorghum bicolor leaf sheaths to treat a variety of ailments, including stroke.

This ancient practice is now being validated by modern science, which has revealed that the variety of Sorghum bicolor used in these treatments has the highest polyphenolic content.

Scientific Validation

The inclusion of Sorghum bicolor in the National Cancer Institute's drug dictionary underscores its potential as an anti-inflammatory and antioxidant agent.

According to the NCI, Sorghum bicolor supplements are rich in polyphenols and possess antioxidant, anti-inflammatory, immunomodulating, and chemopreventive properties.


.Research on Jobelyn

Scientists from the Pharmacology Department at the University of Ibadan, led by Dr. Solomon Umukoro, have conducted studies demonstrating the potential of Jobelyn, a Nigerian herbal product, in providing relief for stroke patients.

Their research, published in the journal Pathophysiology, indicates that Jobelyn may improve neurological function in rats with ischemic stroke by inhibiting oxidative stress and the release of pro-inflammatory cytokines.

Study Reference.

Mechanisms of Action

Ischemic stroke, caused by the sudden obstruction of cerebral blood flow, leads to neuronal cell death and tissue necrosis.

The study by Dr. Umukoro's team suggests that Jobelyn's positive effects on neurological function may be due to its ability to inhibit oxidative stress, reduce neuroinflammation, and prevent neurodegeneration.

The Burden of Stroke

Stroke is the second leading cause of death and disability worldwide.

The lack of accessible, cost-effective treatments in developing countries, particularly in Africa, exacerbates the burden of this disease.

Jobelyn, a dietary supplement derived from the polyphenol-rich leaf sheath of Sorghum bicolor, offers a promising solution.

Benefits of Jobelyn

Manufactured by Health Forever Products Limited in Lagos, Nigeria, Jobelyn is available in capsule form in pharmacies across Nigeria and internationally, including the United States.

It has gained a reputation for treating moderate to severe anemia and is also claimed to be beneficial for neurological disorders such as psychosis, stroke, and convulsions.

Additionally, Jobelyn is known to boost the immune system, enhancing the body's defense mechanisms against stress, infections, and debilitating diseases.

Recommended Dosage

The manufacturer recommends taking one or two capsules of Jobelyn one to three times per day for anemia.

For chronic diseases like cancer, arthritis, and stroke, higher doses are suggested.

Always consult with a healthcare provider before starting any new supplement regimen

Supporting Evidence

The investigation into Jobelyn's effects revealed that it improved neurological deficits caused by bilateral common carotid artery occlusion by inhibiting oxidative stress, neuroinflammation, and neurodegeneration.

These findings support the ethnomedicinal use of Jobelyn as a therapeutic agent for managing ischemic stroke patients.

Stroke and Inflammation

Stroke pathology is closely linked to the activation of oxidative and inflammatory pathways.

Studies have shown that biomarkers of oxidative stress and inflammatory cytokines, such as Interleukin-6 (IL-6), Interleukin-1 (IL-1), and Tumor Necrosis Factor-alpha (TNF-α), increase significantly after the onset of ischemic stroke.

High levels of IL-6 are associated with early neurological deterioration, larger infarct volumes, and poorer long-term outcomes.

Similarly, elevated TNF-α levels correlate with infarct volume and neurological deficits.

During reperfusion, the increase in serum cortisol exacerbates neuronal damage by disrupting glucose homeostasis and increasing oxidative stress in the brain.

This leads to further production of pro-inflammatory cytokines, perpetuating neurodegeneration in stroke-affected brains.

Current treatments using thrombolytic agents are limited as they do not counteract the oxidative and inflammatory damage.

Jobelyn's Neuroprotective Effects

Jobelyn's bioactive compounds, with their potent antioxidant and anti-inflammatory activities, show promise in targeting the multiple pathways involved in stroke pathology.

Experimental studies have demonstrated that Jobelyn mitigates biochemical changes associated with oxidative stress and reduces pro-inflammatory cytokines (IL-6 and TNF-α) in the brain.

It also protects neurons in critical brain regions, supporting motor and cognitive functions.

You are invited to watch the testimony of a stroke patient [ here ]


Stroke is an unpredictable and often severe condition, but emerging research suggests that natural supplements like Jobelyn could offer new hope.

With its potent polyphenolic content and proven benefits in reducing oxidative stress and inflammation, Jobelyn stands out as a promising aid in stroke prevention and recovery.

As always, consult with a healthcare provider to determine if Jobelyn is suitable for your health needs.

Engage with Us

We invite you to share your thoughts and experiences with Jobelyn. Have you tried this supplement?

How has it impacted your health? Leave a comment below and join the conversation.

Don't forget to share this article with friends and family who might benefit from this information.


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